Figure 1: BMP4 and noggin expression in patent and fusing sutures. Figure 2: BMP4-induced Noggin expression in primary osteoblasts and dural cells is suppressed by FGF2 and fgfr2 gain-of-function ...

Two new loci for premature fusion of the cranial sutures in humans suggest a common endpoint in osteoblast regulation, linking upregulation of phosphorylated ERK1/2 and TWIST1 haploinsufficiency.

Researchers are developing technologies to better monitor and treat children with craniosynostosis, a condition that causes the bone plates in the skull to fuse too soon. Engineers and surgeons are ...

Craniosynostosis, the premature fusion of the top of the skull in infants, is caused by an abnormal excess of a previously unknown type of bone-forming stem cell, according to a preclinical study led ...

Craniosynostosis, the premature fusion of the top of the skull in infants, is caused by an abnormal excess of a previously unknown type of bone-forming stem cell, according to a preclinical study led ...

Metopic craniosynostosis is a rare condition in infants in which a certain part of the skull fuses earlier than it typically would. The condition can range from mild to severe and cause long-term ...

Have you ever seen a baby wearing headgear that looked like a helmet? They may be doing helmet therapy or cranial orthosis. Some babies who require helmet therapy have a condition called ...

Brad Amendt, professor of anatomy and cell biology, professor of orthodontics at the University of Iowa, and the study’s corresponding author. University of Iowa researchers have successfully tested a ...