When developing antibody-drug conjugates (ADCs), the linker structure significantly influences stability, homogeneity, cytotoxic potency, tolerability, and pharmacokinetics (PK). Selecting the right ...

Surprisingly, a material with some more easily broken bonds is harder to tear. Chemists from MIT and Duke University have discovered a counterintuitive way to make polymers stronger. Working with ...

Over the last several decades, mounting interest has positioned bioconjugate therapeutics as one of the most promising biopharmaceutical modalities. Work in chemical biology, including novel ...