This protocol describes a practical laboratory-scale method for aerobic oxidation of primary alcohols to aldehydes, using a chemoselective Cu I /TEMPO (TEMPO = 2,2,6,6-tetramethyl-1-piperidinyloxyl) ...
DESPITE THEIR FUNDAMENTAL ROLE in chemical and biochemical systems, amides are tough to make. Routes to this functional group usually employ toxic reagents, such as thionyl chloride; require corrosive ...
Few functional groups are as popular in synthesis as the carbonyl group. Composed of an oxygen molecule doubly bonded to carbon, the carbonyl welcomes reaction with all types of nucleophiles.