Gut

Fibroblast pentose phosphate pathway activation upon decreased circPLCE1 exacerbates intestinal fibrosis in Crohn’s disease

Background Intestinal fibrosis, a hallmark complication of Crohn’s disease (CD), frequently progresses to stricture formation ...
Gut

Effects of a probiotic fermented dairy product on hippocampal metabolites, structure and function: an 8-week randomised, placebo-controlled trial in healthy women

Background Fermented foods are a promising yet underexplored intervention for influencing brain function and mental health through the gut–brain axis. Objective The objective of this study was to ...
Gut

Response to ‘Rectal versus colonic submucosal cancer rates and procedural outcomes in large non-pedunculated polyps: French ESD registry data’

We read with great interest the study by Van der Voort et al ,1 which compared rectal versus colonic submucosal cancer rates ...
GutOpinion

Red cells, red flags: are we harming stable patients with outdated transfusion thresholds?

The 2022 UK-wide acute upper gastrointestinal bleeding (AUGIB) audit by Nigam and colleagues is a landmark. With ...
gut.bmj

Setting a vision for British Society of Gastroenterology guidelines: embracing innovation while preserving methodological excellence and clinical utility

Correspondence to Dr Matthew Kurien, Division of Clinical Medicine, School of Medicine & Population Health, The University of Sheffield Faculty of Medicine Dentistry and Health, Sheffield, South ...
gut.bmj

HBsAg seroclearance after nucleoside analogue therapy in patients with chronic hepatitis B: clinical outcomes and durability

Department of Gastroenterology, Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea Correspondence to Professor Young-Suk Lim, Department of ...
gut.bmj

Apoptosis: a mechanism of acute and chronic liver injury

Correspondence to: Dr G J Gores Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA; gores.gregorymayo.edu ...
gut.bmj

A randomised, double blind, multicentre trial of octreotide in moderate to severe acute pancreatitis

Professor M W Büchler, Department of Visceral and Transplantation Surgery, University Hospital of Bern, Inselspital, CH-3010 Bern, Switzerland. BACKGROUND The pharmacological inhibition of exocrine ...
gut.bmj

Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification

Dr L Lundell, Department of Surgery, Sahlgrenska University Hospital, S-413 45 Göteborg, Sweden. BACKGROUND Endoscopic oesophageal changes are diagnostically helpful and identify patients exposed to ...
gut.bmj

Peripheral arthropathies in inflammatory bowel disease: their articular distribution and natural history

Background—Peripheral arthropathy is a well-recognised complication of inflammatory bowel disease (IBD). Little is known of its natural history, but a variety of joint involvement has been described, ...
gut.bmj

EUS versus MRCP to perform ERCP in patients with intermediate likelihood of choledocholithiasis: a randomised controlled trial

Objective In patients with an intermediate likelihood of choledocholithiasis, European Society of Gastrointestinal Endoscopy (ESGE) guidelines recommend endoscopic ultrasound (EUS) or magnetic ...
gut.bmj

Yin Yang 1 promotes hepatic steatosis through repression of farnesoid X receptor in obese mice

1 Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrinology and Metabolism, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China 2 Genomic ...