The 49ers definitely will be without defensive tackle Kevin Givens (groin), punter Mitch Wishnowsky (back) and cornerback ...

Left tackle Trent Williams (ankle), defensive end Nick Bosa (hip) and tight end George Kittle (hamstring) are questionable.

Two 49ers stars are questionable for San Francisco's NFC West showdown against the Seattle Seahawks on Sunday at Levi's ...

What to look for from the top 49ers and Seahawks players and how to watch the game as they face off on Sunday, week 11.

The San Francisco 49ers are teetering on the brink of potential disaster on the injury front as they prepare for their Week ...

Kittle injured his hamstring during the 49ers’ Week 10 win over the Tampa Bay Buccaneers. Shanahan told reporters in a press ...

San Francisco 49ers tight end George Kittle has two objectives for this season — remain healthy and win a Super Bowl.

The Seattle Seahawks will visit the San Francisco 49ers in a key game in the NFC West race with both teams trying to catch ...

San Francisco 49ers WAG Clair Kittle and husband George Kittle have teamed up for a new eyeglasses line to bring extra swag ...

The 49ers do not have tight end George Kittle (hamstring) and edge rusher Nick Bosa (hip) in Wednesday's practice.

Brock Purdy takes a 5-0 record against the Seahawks into Sunday’s game, while counterpart Geno Smith looks for his first win ...