The EMBO Journal4d
Experience-driven development of decision-related representations in the auditory cortex
Tracking the activity in the auditory cortex as mice gain experience in a tone detection task with a delayed decision window ...
The EMBO Journal6d
Hair follicle stem cells and the collapse of self-tolerance in alopecia: the interplay of barrier function, the microbiome, and immunity
The hair follicle is a dynamic miniature organ. Its permanent portion opens to the skin surface, communicates with sebaceous ...
The EMBO Journal11d
Rett syndrome: interferon-γ to the rescue?
In conclusion, this intriguing report builds on the work of many other groups by further unraveling MECP2 function in the ...
The EMBO Journal5d
The winter holidays are glorious—except when they’re not
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...
The EMBO Journal10d
Making contact away from home: a bacterial secreted effector mediates inter-organelle communication
Inter-organelle communication via the formation of membrane contact sites (MCS) is essential for cell homeostasis. Bacterial pathogens residing in membrane bound vacuoles have exploited this ...
The EMBO Journal11d
Severe fever with thrombocytopenia syndrome virus induces lactylation of m6A reader protein YTHDF1 to facilitate viral replication
YTHDF1 binds to m6A modification sites on SFTSV, decreasing the stability of SFTSV RNA and reducing translation efficiency of SFTSV proteins. SFTSV protein NSs promotes YTHDF1 lactylation to inhibit ...
The EMBO Journal5d
Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Hormone therapy resistance and the ensuing ...
The EMBO Journal26d
Glutamine sensing licenses cholesterol synthesis
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The mevalonate pathway produces essential ...
The EMBO Journal6d
Circadian rhythms of macrophages are altered by the acidic tumor microenvironment
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Tumor-associated macrophages (TAMs) are prime ...
The EMBO Journal8d
Structural basis of 3′-tRNA maturation by the human mitochondrial RNase Z complex
a Gold-standard 0.143 FSC resolution calculated with 3DFSC (Tan et al, 2017). The masks for FSC calculation were generated in CryoSPARC using a relative threshold of 0.5. b Gold-standard 0.143 FSC ...
The EMBO Journal7d
JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The hair follicle stem cell niche is an immune ...